Conventional and extended intramammary therapy of persistent subclinical mastitis using nafcillin-penicillindihydrostreptomycin in lactating dairy cattle

Authors

  • A. Barin Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
  • F. Gharagozlou Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
  • H. A. Seifi Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran
  • M. Bolourchi Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
  • N. Farzaneh Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran
  • P. Hovareshti Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
  • R. Kasravi Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Abstract:

The objective of the present study was to compare the efficacy of conventional and extendedintramammary (IMM) therapy of persistent subclinical mastitis in lactating dairy cattle using nafcillinpenicillin-dihydrostreptomycin combination (NPD). Sixty-five dairy cows with 126 infected quarters were enrolled in the study. Infected cows were allocated randomly to 1 of 3 different treatment regimens: (1) conventional group: NPD administered IMM 3 times at 24-h intervals (20 infected cows, 43 intramammaryinfections [IMI]), (2) extended group: NPD administered IMM 6 times at 24-h intervals (23 cows, 43 IMI),and (3) untreated control group (22 cows, 40 IMI). The overall bacteriological cure (BC) rates for subclinicalIMI were 86.04%, 100%, and 20% for the conventional, extended and the control groups, respectively;indicating a higher BC rate (P

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Journal title

volume 12  issue 2

pages  113- 120

publication date 2011-06-20

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